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| Designation | Principal Scientist |
| Discipline | Veterinary Microbiology |
| Division | Finfish Culture Division |
| Specialization | Fish Immunology |
| Phone | +91- 044 – 24618817 Ext: 410 |
| M.Makesh@icar.gov.in | |
| Google Scholar | Click Here |
| Research Gate | Click Here |
- Brief Profile
- Research areas
- Current Research Projects
- Recognition (National & International)
- Best 5 Publications during the Career
- Best 3 Publications during last 3 years
After my master’s degree in Veterinary Microbiology in 1997 and Ph.D. in Veterinary Microbiology in 2005, I served at ICAR-Central Institute of Fisheries Education, Mumbai. I have guided 11 Master’s degree and 4 doctoral students as the chairman of the advisory committee. I’m currently working in Fish Culture Division at ICAR-CIBA, Chennai since 2015. My field of work is fish and crustacean immunology and virology and have contributed to the development of molecular and immunodiagnostics for fish and shellfish diseases. I have developed hybridoma clones secreting monoclonal antibodies against several fish IgM and fish pathogens. I have interests in the mucosal immunity of fish, development of oral and immersion vaccines, and diagnostics for fish diseases.
- Fish Virology
- Fish Immunology
- Mucosal immunity
- Oral and immersion delivery of fish vaccines and drugs
| No | Title | Funded By |
|---|---|---|
| 1 | Development of recombinant microalgae expressing Nervous necrosis virus capsid protein for vaccinating finfish against viral nervous necrosis | ICAR |
| 2 | All India Network project on fish health | ICAR |
| 3 | Development of nanoemulsion based delivery of drugs for treatment of bacterial and parasitic diseases of brackishwater fish | ICAR |
| 4 | Studies on ontogeny and expression of immune genes of Asian seabass and milkfish. In vitro and in vivo transcriptome profiling of NNV infected Asian seabass and milk fish seeds | ICAR |
- DBT-CREST fellowship for the year 2012-13 for ‘Studies on
Mucosal immune response in fish’ at Department of Fish and Wildlife Resources, College of Natural Resources, University of Idaho, Moscow, Idaho 83844-1136, USA - Best oral presentation award in Braqcon for the Paper presented at Braqcon 2019, World Brackishwater Aquaculture Conference organized by Society of Coastal Aquaculture and Fisheries (SCAFi) and Central Institute of Brackishwater Aquaculture, Chennai during 22-25, January 2019 at ICAR-CIBA, Chennai.
- Makesh, M., Koteeswaran, A., Chandran, N. Daniel Joy, Manohar, B. Murali, Ramasamy, V., 2006. Development of monoclonal antibodies against VP28 of WSSV and its application to detect WSSV using immunocomb. Aquaculture, 261:64-71.
- Manas Ranjan Bag, M. Makesh, K.V. Rajendran, S.C. Mukherjee. 2009. Characterization of IgM of Indian major carps and their cross- reactivity with anti-fish IgM antibodies. Fish and shellfish Immunology. 26:275-278.
- Pushpa K, P. Gireesh-Babu, K. V. Rajendran, C. S. Purushothaman, S. Dasgupta, M. Makesh. 2014. Molecular cloning, sequencing and tissue-level expression of complement C3 of Labeo rohita (Hamilton, 1822). Fish and Shellfish Immunology 40: 319-330.
- Makesh M, Ponnerassery S. Sudheesh, Kenneth D. Cain. 2015. Systemic and mucosal immune response of rainbow trout to immunization with an attenuated Flavobacterium psychrophilum vaccine strain by different routes. Fish & Shellfish Immunology, 44; 156-163.
- Husne Banu, Deepika Anand, Megha Bedekar, K V Rajendran & M. Makesh. 2017. Monoclonal antibodies against recombinant GAPDH of Edwardsiella tarda reveal the conserved nature of the protein. Food and Agricultural Immunology.28: 685–698.
- Nallala, V.S., Makesh, M., Radhika, K., Sathish Kumar, T., Raja, P., Subburaj, R., Kailasam, M., Vijayan, K.K. 2021. Characterization of red-spotted grouper nervous necrosis virus isolated from ovarian fluids of asymptomatic wild Asian seabass, Lates calcarifer. Aquaculture 542: 736846.
- Satyanarayana N.V., Makesh M., Sain, A., Jayaprakash N.S., Kailasam M., Vijayan K.K. 2021. Non-lethal screening of Asian seabass (Lates calcarifer) by monoclonal antibody based indirect enzyme linked immunosorbent assay for viral nervous necrosis. Fish and Shellfish Immunology Reports. 2; 2021: 100011.
- Makesh, N. Venkata Satyanarayana, S. Selvamano, N.S. Jayaprakash, Aritra Bera, Krishna Sukumaran, M. Kailasam. 2022. Nervous necrosis virus titration and antigen quantitation by indirect sandwich enzyme linked immunosorbent assay. Journal of Virological Methods 305; 114536.